Acute blood loss anaemia
Rule blood_loss_anemia version 2026.11-1 · condition: Acute blood loss anaemia
Published source
WHO guideline on haemoglobin cutoffs to define anaemia in individuals and populations (2024). Adult cut-offs: men <13 g/dL, non-pregnant women <12 g/dL (unchanged from 2011). https://thebloodproject.com/definition-of-anemia-hb-thresholds/ · public page checked 2026-11-14
WHO PDF not loadable during verification; thresholds verified from a secondary page citing it.
Also: ISTH definition of major bleeding in non-surgical patients (Schulman and Kearon, J Thromb Haemost 2005;3:692-694) (2005). Fall in haemoglobin of 2 g/dL or more, or transfusion of 2 or more units. link
Contested or local convention. There is no published clinical definition of "acute blood loss anaemia". This rule is a LOCAL CONVENTION: WHO anaemia threshold at the nadir, a documented bleeding source, and an acute fall of >=2 g/dL OR >=2 units transfused (borrowed from the ISTH major-bleeding definition, which secondary restatements word inconsistently as AND/OR).
Inputs
- sex
- Sex
- hgb_first
- First haemoglobin this stay (g/dL)
- hgb_nadir
- Lowest haemoglobin this stay (g/dL)
- hgb_drop
- Highest value before the nadir minus the nadir (g/dL)
- prbc_units
- Red cell units transfused
- bleeding_documented
- A bleeding source quoted from a note, or a bleeding principal diagnosis
Thresholds
- t.hb_m
- 13
- t.hb_f
- 12
- t.drop_major
- 2.0
- t.drop_min
- 1.0
- t.prbc_major
- 2
Derived values
| Name | Expression |
|---|---|
| anaemic | case(sex == 'M', hgb_nadir < t.hb_m, sex == 'F', hgb_nadir < t.hb_f, null) |
| acute_fall | hgb_drop >= t.drop_major or prbc_units >= t.prbc_major |
Outcomes
| Outcome | When | Status | Supports |
|---|---|---|---|
| met Haemoglobin fell {hgb_drop} g/dL to {hgb_nadir} with {prbc_units} unit(s) transfused and a documented bleeding source | bleeding_documented and anaemic and acute_fall | supported | D62 Acute blood loss anemia |
| anaemia_only Anaemia (nadir {hgb_nadir}) without an acute fall or transfusion | anaemic and hgb_drop < t.drop_min and prbc_units == 0 | supported | D64.9 Anemia (acute blood-loss criteria not met) |
| not_anaemic Haemoglobin nadir {hgb_nadir} g/dL is above the WHO anaemia threshold | present(hgb_nadir) and not anaemic | not_supported | — |
| no_source Acute haemoglobin fall without a documented bleeding source | anaemic and acute_fall | judgement | — |
| borderline Haemoglobin fell {hgb_drop} g/dL without transfusion (between 1 and 2 g/dL) | anaemic | judgement | — |
ICD-10-CM specificity ladder (FY2026 CC/MCC status as a secondary diagnosis)
- D64.9 Anemia, unspecified · non-CC
- D62 Acute posthemorrhagic (blood loss) anemia · CC (refines D64.9)
Query topic: hematology documentation · prompts for an undocumented diagnosis: yes
Where clinical judgement is required
- Expected operative blood loss versus acute blood loss anaemia is a clinician judgement the rule does not make.