Definition library

In our words: No measurement-only definition is stored; oxygenation bands are in the two ARDS entries.

cited source; wording is ours (numbers restated, no text reproduced). No endorsement by the cited bodies is implied.

In our words: Hyperosmolar state: no acidosis (pH 7.3 or higher and bicarbonate 18 mmol/L or higher); glucose and osmolality cut-offs not verified.

ADA, EASD, JBDS, AACE and DTS (Diabetes Care 2024;47:1257-1275) (2024) · Section 4 · source

cited source; wording is ours (numbers restated, no text reproduced). No endorsement by the cited bodies is implied.

In our words: Severity: β-hydroxybutyrate 3.0 to 6.0 mmol/L mild or moderate, above 6.0 severe; pH above 7.25 to below 7.30 mild, 7.0 to 7.25 moderate, below 7.0 severe; bicarbonate 15 to 18 mild, 10 to below 15 moderate, below 10 mmol/L severe.

ADA, EASD, JBDS, AACE and DTS (Diabetes Care 2024;47:1257-1275, doi:10.2337/dci24-0032) (2024) · Table 2 'DKA classification and suggested level of care by severity' · source

cited source; wording is ours (numbers restated, no text reproduced). No endorsement by the cited bodies is implied.

In our words: Same categories as the federal NHLBI page (see nhlbi_bp_categories); nothing stored from the guideline.

cited source; wording is ours (numbers restated, no text reproduced). No endorsement by the cited bodies is implied.

In our words: Severe malnutrition, acute illness: at least two of intake at or below half of need for 5 days or more; weight loss over 2% in a week, over 5% in a month or over 7.5% in 3 months; moderate fat or muscle loss; moderate to severe fluid; reduced grip.

White JV, Guenter P, Jensen G, Malone A, Schofield M (J Acad Nutr Diet 2012;112:730-738; JPEN 2012, doi:10.1177/0148607112440285) (2012) · Table of clinical characteristics

cited source; wording is ours (numbers restated, no text reproduced). No endorsement by the cited bodies is implied.

In our words: Adverse-event grade by management, not by value; nothing executable.

TSH increased and no intervention initiated

National Cancer Institute, Cancer Therapy Evaluation Program (U.S. Department of Health and Human Services) (2017) · PDF page 89 (5x7 quick reference), term 'Thyroid stimulating hormone increased' (published November 27, 2017) · source

retired: Retired with the CTCAE entries: an adverse-event grading scale for cancer treatment, not a diagnostic definition. No endorsement by the cited bodies is implied.

In our words: Adverse-event grade by management, not by value; nothing executable.

Grade 1: Laboratory finding only and intervention not indicated. Grade 2: Oral replacement therapy indicated

National Cancer Institute, Cancer Therapy Evaluation Program (U.S. Department of Health and Human Services) (2025) · PDF page 181, term 'Hypophosphatemia' (published July 22, 2025) · source

retired: Retired with the CTCAE entries: an adverse-event grading scale for cancer treatment, not a diagnostic definition. No endorsement by the cited bodies is implied.

In our words: Diagnosed clinically; no measurement-only definition is stored.

cited source; wording is ours (numbers restated, no text reproduced). No endorsement by the cited bodies is implied.

In our words: Severity bands not opened; only the below-135 mmol/L definition is executable.

cited source; wording is ours (numbers restated, no text reproduced). No endorsement by the cited bodies is implied.

In our words: Not opened (payment required); nothing stored.

cited source; wording is ours (numbers restated, no text reproduced). No endorsement by the cited bodies is implied.

In our words: Combines biomarker results with clinical evidence; no threshold stored.

ESC/ACC/AHA/WHF joint task force (J Am Coll Cardiol 2018;72:2231-2264) (2018) · citation record only (Europe PMC, PMID:30153967); full text not opened · source

cited source; wording is ours (numbers restated, no text reproduced). No endorsement by the cited bodies is implied.

In our words: GLIM: at least one physical finding (weight loss over 5% in 6 months or over 10% longer; low BMI; low muscle mass) and one cause (eating half or less of needs for over a week, or less for over 2 weeks; inflammation). Severe: weight loss over 10% in 6 months or over 20% longer, or BMI below 18.5 under 70 / below 20 at 70 and over.

>5% within past 6 months, or>10% beyond 6 months | <20 if <70 years, or <22 if >70 years | Asia: <18.5 if <70 years, or <20 if >70 years | ≤50% of ER >1 week, or any reduction for >2 weeks

Cederholm T et al., GLIM Core Leadership Committee and Working Group (J Cachexia Sarcopenia Muscle 2019;10(1):207-217, doi:10.1002/jcsm.12383) (2019) · Table 3 (phenotypic and etiologic criteria); Table 4 (severity); section 3.8 (diagnosis rule) · source

open licence: CC BY 4.0, attribution: Cederholm T et al. GLIM criteria for the diagnosis of malnutrition - A consensus report from the global clinical nutrition community. J Cachexia Sarcopenia Muscle 2019;10(1):207-217, doi:10.1002/jcsm.12383. Licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). No endorsement by the cited bodies is implied.

In our words: No oxygen-saturation definition opened; nothing stored.

cited source; wording is ours (numbers restated, no text reproduced). No endorsement by the cited bodies is implied.

In our words: CKD: eGFR below 60, or urine albumin-to-creatinine ratio 30 mg/g or higher, on tests at least 3 months apart. eGFR from the 2021 race-free creatinine equation. AKI: creatinine up at least 0.3 mg/dL in 48 hours, or to at least 1.5 times baseline within 7 days, or low urine output for 6 hours.

Decreased eGFR <60 mL/min/1.73 m2 (GFR categories G3a-G5) for ≥3 months | Albuminuria (UACR ≥30 mg/g) on at least two measurements separated by ≥3 months

U.S. Department of Veterans Affairs and Department of Defense (2025) · Sidebar 2A 'eGFR Calculation' (PDF p. 10); Sidebar 4 'Definition of AKI and AKD' (PDF p. 13); Sidebar 6 'Criteria for CKD' (PDF p. 16) · source

U.S. government work (public domain). No endorsement by the cited bodies is implied.

In our words: Stages are judged by looking at the wound (from intact skin with redness that does not blanch to full-thickness loss); there is no measurement.

National Pressure Injury Advisory Panel (2016) · NPIAP sheet 'Pressure Injury and Stages' (© September 2016), Stage 1 definition; the NPIAP staging web page refused automated access (HTTP 403) on 2026-11-14, so the deep link could not be confirmed · source

cited source; wording is ours (numbers restated, no text reproduced). No endorsement by the cited bodies is implied.

In our words: Sepsis: suspected infection with a rise of 2 or more SOFA points. Septic shock adds vasopressors to keep mean pressure at 65 mm Hg or more and lactate above 2 mmol/L after fluids.

SCCM and ESICM task force (JAMA 2016;315:801-810) (2016) · Box 3 'New Terms and Definitions' · source

cited source; wording is ours (numbers restated, no text reproduced). No endorsement by the cited bodies is implied.

In our words: Stage (at risk, pre-HF, HF, advanced HF) and acuity are clinical judgements; the record values are shown for review.

at risk for HF, pre‐HF, HF, and advanced HF in place of the previous stages A–D

Chandramouli C, Stewart S, Almahmeed W, Lam CSP (Clin Cardiol 2022;45(Suppl 1):S2-S12, doi:10.1002/clc.23842) (2022) · Section 1.3 'New universal definition' (stages); section 2.4 (trajectory terms) · source

open licence: CC BY 4.0, attribution: Chandramouli C, Stewart S, Almahmeed W, Lam CSP. Clinical implications of the universal definition for the prevention and treatment of heart failure. Clin Cardiol 2022;45(Suppl 1):S2-S12, doi:10.1002/clc.23842. Licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). No endorsement by the cited bodies is implied.

In our words: No cobalamin cut-off opened; nothing stored.

cited source; wording is ours (numbers restated, no text reproduced). No endorsement by the cited bodies is implied.

In our words: Lower BMI action points for Asian populations were not opened; nothing stored (WHO non-commercial licence if ever encoded).

cited source; wording is ours (numbers restated, no text reproduced). No endorsement by the cited bodies is implied.