Staff surface Definitions and reviews
Definition library
Every executable definition and catalogue entry, with the threshold quoted from its source. All are drafts pending
clinical and coding review; a definition shows as reviewed only after an approval is recorded. Default set library_default_set@1.0.
Coder worklist
- ≡66 entries
- ✓0 reviewed
- ≠0 changes requested
- ◇66 pending review
Cancer-treatment adverse-event grading scale (NCI CTCAE): off by default
CTCAE grades describe adverse events in people receiving cancer treatment, usually in trials; they are not diagnostic criteria, and several grades depend on the laboratory reference range or on clinical descriptors that are not encoded. Using them outside that setting is a local decision for the clinical reviewer.
Current: Off (default)
When on, grading entries are shown only as "another published definition gives …" or as values needing clinical judgement; they never
raise a "not stated" item.
CDI or coding staff can change this setting and record reviews: switch the demo user.
18 of 66 shown · open an entry for its source, threshold and review.
Acute respiratory failure acute_respiratory_failure
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Acute respiratory failure
- Tier
- 2
- Use here
- catalogue (not executable)
- Edition
- Why not executable
- Source not opened: no authoritative numeric definition of acute respiratory failure was opened, so no blood-gas threshold is recorded. The diagnosis also rests on work of breathing and clinical context.
source not opened,
acute_respiratory_failure
Source not opened.
Review
No review recorded yet.
Hyperosmolar hyperglycaemic state ada2024_hhs
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- HHS
- Tier
- 2
- Use here
- catalogue (not executable)
- Edition
- 2024
- Why not executable
- Part of the 2024 hyperglycaemic crises consensus (see ada2024_hyperglycaemic_crises): the diagnostic figure was not readable in the opened text; the text says 'All four components must be present' and gives 'without acidosis (pH ≥7.3 and bicarbonate ≥18 mmol/L)'. Not executable until the figure is opened.
ADA, EASD, JBDS, AACE and DTS (Diabetes Care 2024;47:1257-1275), Hyperglycemic Crises in Adults With Diabetes: A Consensus Report
ada2024_hhs
without acidosis (pH ≥7.3 and bicarbonate ≥18 mmol/L)
2024 · Section 4 · source
Review
No review recorded yet.
Diabetic ketoacidosis and hyperosmolar hyperglycaemic state (ADA/EASD/JBDS/AACE/DTS consensus 2024) ada2024_hyperglycaemic_crises
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- DKA / HHS
- Tier
- 2
- Use here
- catalogue (not executable)
- Edition
- 2024
- Why not executable
- The diagnostic criteria are in the consensus report's Figure 2, which was not readable in the opened text; the severity table (Table 2) says 'Not all variables need to be fulfilled' and includes mental status, and its bicarbonate bands overlap at 15 mmol/L (mild 15–18, moderate 10 to <15). Not executable until Figure 2 is opened and the overlaps are resolved by a clinician.
ADA, EASD, JBDS, AACE and DTS (Diabetes Care 2024;47:1257-1275, doi:10.2337/dci24-0032), Hyperglycemic Crises in Adults With Diabetes: A Consensus Report
ada2024_hyperglycaemic_crises
Not all variables need to be fulfilled to be defined as either mild, moderate, or severe
2024 · Table 2 'DKA classification and suggested level of care by severity' · source
Review
No review recorded yet.
2025 AHA/ACC blood pressure categories table (guideline text itself) aha2025_bp_table
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Hypertension
- Tier
- 1
- Use here
- catalogue (not executable)
- Edition
- Why not executable
- Source not opened: the guideline (Hypertension 2025;82:e212-e316; Circulation 2025;152:e114-e218) and the AHA patient page refused automated access (HTTP 403). The same categories are executable from the NHLBI page (nhlbi_bp_categories), with the 130/80 threshold confirmed by an open-access commentary.
source not opened,
aha2025_bp_table
Source not opened.
Review
No review recorded yet.
Thyroid stimulating hormone increased (CTCAE v5.0) and thyroid dysfunction by TSH ctcae5_tsh_increased
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Thyroid dysfunction
- Tier
- 2
- Use here
- catalogue (not executable)
- Edition
- 2017
- Why not executable
- TSH thresholds depend on the laboratory reference range, age and pregnancy, and hypothyroidism/hyperthyroidism also need free T4/T3 and clinical context. CTCAE v5.0 grades only 'TSH increased and no intervention initiated' (grade 1) and sends anything treated to 'Hypothyroidism'. Without the laboratory range and free hormone levels the answer would be 'not assessable', so no executable entry is offered. No guideline with fixed TSH cut-offs was opened.
National Cancer Institute, Cancer Therapy Evaluation Program (U.S. Department of Health and Human Services), Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0
ctcae5_tsh_increased
TSH increased and no intervention initiated
2017 · PDF page 89 (5x7 quick reference), term 'Thyroid stimulating hormone increased' (published November 27, 2017) · source
Review
No review recorded yet.
Hypophosphataemia grade (CTCAE v6.0) ctcae6_hypophosphataemia
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Hypophosphataemia
- Tier
- 2
- Use here
- catalogue (not executable)
- Edition
- 2025
- Why not executable
- CTCAE v6.0 grades hypophosphataemia by management, not by value: grade 1 'Laboratory finding only and intervention not indicated', grade 2 'Oral replacement therapy indicated', grade 3 hospitalisation, grade 4 life-threatening. No numeric threshold to execute. No other numeric definition was opened.
National Cancer Institute, Cancer Therapy Evaluation Program (U.S. Department of Health and Human Services), Common Terminology Criteria for Adverse Events (CTCAE) v6.0 (MedDRA 28.0)
ctcae6_hypophosphataemia
Grade 1: Laboratory finding only and intervention not indicated. Grade 2: Oral replacement therapy indicated
2025 · PDF page 181, term 'Hypophosphatemia' (published July 22, 2025) · source
Review
No review recorded yet.
Encephalopathy (metabolic, toxic, septic) encephalopathy
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Encephalopathy
- Tier
- 3
- Use here
- catalogue (not executable)
- Edition
- Why not executable
- Encephalopathy is diagnosed clinically (altered mental status with a cause); no measurement-based definition from an authoritative body was opened. Source not opened.
source not opened,
encephalopathy
Source not opened.
Review
No review recorded yet.
Hyponatraemia severity and timing (ESE/ESICM/ERA-EDTA 2014) ese2014_hyponatraemia_severity
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Hyponatraemia
- Tier
- 1
- Use here
- catalogue (not executable)
- Edition
- Why not executable
- Source not opened: the guideline's severity bands (mild, moderate, profound) and acute/chronic classification are in the full text, which could not be opened (publisher pages refused or returned server errors; not open access in Europe PMC). Only the <135 mmol/L definition from the abstract is executable (ese2014_hyponatraemia).
source not opened,
ese2014_hyponatraemia_severity
Source not opened.
Review
No review recorded yet.
Hypertension grades 1-3 (ESH 2023) esh2023_bp_grades
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Hypertension
- Tier
- 1
- Use here
- catalogue (not executable)
- Edition
- Why not executable
- Source not opened: the 2023 ESH guideline (J Hypertens 2023;41:1874) returned HTTP 402 (payment required). Not encoded; ESC 2024 office categories are executable as esc2024_office_bp.
source not opened,
esh2023_bp_grades
Source not opened.
Review
No review recorded yet.
Myocardial infarction (Fourth Universal Definition, 2018) fourth_udmi2018_myocardial_infarction
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Myocardial infarction
- Tier
- 2
- Use here
- catalogue (not executable)
- Edition
- 2018
- Why not executable
- Source not opened: only the citation record was found (no abstract or full text readable on 2026-11-14). Myocardial infarction definitions combine biomarker results with clinical evidence of ischaemia, which numbers alone cannot decide; no threshold is recorded here.
ESC/ACC/AHA/WHF joint task force (J Am Coll Cardiol 2018;72:2231-2264), Fourth Universal Definition of Myocardial Infarction (2018)
fourth_udmi2018_myocardial_infarction
Source not opened.
2018 · citation record only (Europe PMC, PMID:30153967); full text not opened · source
Review
No review recorded yet.
Malnutrition (GLIM criteria) glim2019_malnutrition
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Malnutrition
- Tier
- 2
- Use here
- catalogue (not executable)
- Edition
- 2019
- Why not executable
- Diagnosis needs at least one phenotypic and one etiologic criterion. Reduced muscle mass needs a validated body-composition method or examination, and the etiologic criteria (reduced intake or assimilation, inflammation from acute or chronic disease) are clinical judgements. GLIM also requires prior risk screening. Numbers alone cannot decide it.
Global Leadership Initiative on Malnutrition (ASPEN, ESPEN, FELANPE, PENSA) — Clin Nutr 2019;38:1-9, GLIM criteria for the diagnosis of malnutrition – A consensus report from the global clinical nutrition community
glim2019_malnutrition
>5% within past 6 months, or >10% beyond 6 months | <20 if < 70 years, or <22 if >70 years | Asia: <18.5 if < 70 years, or <20 if >70 years
2019 · Table 3 Phenotypic and etiologic criteria for the diagnosis of malnutrition · source
Review
No review recorded yet.
Hypoxaemia by SpO2 or PaO2 hypoxaemia_spo2_pao2
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Hypoxaemia
- Tier
- 1
- Use here
- catalogue (not executable)
- Edition
- Why not executable
- Source not opened: no oxygen-therapy guideline defining hypoxaemia by SpO2 or PaO2 was opened. PaO2/FiO2 bands are executable within the ARDS definitions.
source not opened,
hypoxaemia_spo2_pao2
Source not opened.
Review
No review recorded yet.
Acute kidney injury and chronic kidney disease (KDIGO) kdigo_aki_ckd
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- AKI / CKD
- Tier
- 1
- Use here
- catalogue (not executable)
- Edition
- Why not executable
- Executable already, outside this library: apps/exactdx/rules/kidney (kdigo_aki_2012@1.0, kdigo_ckd_2024@1.0 with the CKD-EPI equations). Not duplicated here; the KDIGO texts were not re-opened for this library.
source not opened,
kdigo_aki_ckd
Source not opened.
Review
No review recorded yet.
Pressure injury staging (NPIAP 2016) npiap2016_pressure_injury_stages
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Pressure injury
- Tier
- 3
- Use here
- catalogue (not executable)
- Edition
- 2016
- Why not executable
- Stages are defined by what the wound looks like on examination (intact skin with non-blanchable erythema, partial-thickness loss, full-thickness loss, exposed fascia or bone, slough or eschar obscuring the base, deep tissue injury). There is no measurement to compute.
National Pressure Injury Advisory Panel, Pressure Injury and Stages (staging illustrations and definitions)
npiap2016_pressure_injury_stages
Stage 1 Pressure Injury: Non-blanchable erythema of intact skin
2016 · NPIAP sheet 'Pressure Injury and Stages' (© September 2016), Stage 1 definition; the NPIAP staging web page refused automated access (HTTP 403) on 2026-11-14, so the deep link could not be confirmed · source
Review
No review recorded yet.
Sepsis and septic shock (Sepsis-3) sepsis3_sepsis_and_septic_shock
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Sepsis / septic shock
- Tier
- 2
- Use here
- catalogue (not executable)
- Edition
- 2016
- Why not executable
- Sepsis needs suspected or documented infection and an acute change in total SOFA score of 2 points or more consequent to the infection; septic shock adds vasopressor-dependent hypotension and lactate >2 mmol/L after adequate volume resuscitation. Infection, attribution and adequacy of resuscitation are clinical judgements; SOFA needs six organ systems including the Glasgow Coma Scale.
SCCM and ESICM task force (JAMA 2016;315:801-810), The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
sepsis3_sepsis_and_septic_shock
Organ dysfunction can be identified as an acute change in total SOFA score ≥2 points consequent to the infection.
2016 · Box 3 'New Terms and Definitions' · source
Review
No review recorded yet.
Heart failure acuity and stage uhf2021_hf_acuity_and_stage
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Heart failure acuity
- Tier
- 2
- Use here
- catalogue (not executable)
- Edition
- 2021
- Why not executable
- The universal definition's stages (A at risk, B pre-HF, C symptomatic HF, D advanced HF) and acuity (acute, chronic, acute on chronic) depend on symptoms, signs, structural disease and response to therapy. Only the EF category is numeric and is executable as uhf2021_hf_ef_category.
HFSA, HFA-ESC and JHFS (J Card Fail 2021;27:387-413), Universal Definition and Classification of Heart Failure
uhf2021_hf_acuity_and_stage
HF is a clinical syndrome with symptoms and or signs caused by a structural and/or functional cardiac abnormality and corroborated by elevated natriuretic peptide levels and or objective evidence of pulmonary or systemic congestion.
2021 · Abstract · source
Review
No review recorded yet.
Vitamin B12 deficiency vitamin_b12_deficiency
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Vitamin B12 deficiency
- Tier
- 1
- Use here
- catalogue (not executable)
- Edition
- Why not executable
- Source not opened: no guideline stating serum cobalamin cut-offs was opened (thresholds are assay-dependent and contested; methylmalonic acid and holotranscobalamin are often needed). Not encoded.
source not opened,
vitamin_b12_deficiency
Source not opened.
Review
No review recorded yet.
BMI action points for Asian populations (WHO expert consultation 2004) who2004_asian_bmi
catalogue
Draft · pending review draft — pending clinical and coding review
- Status
- draft — pending clinical and coding review (draft — requires clinical and coding review)
- Condition
- Obesity / overweight
- Tier
- 1
- Use here
- catalogue (not executable)
- Edition
- Why not executable
- Source not opened: the WHO expert consultation (Lancet 2004;363:157-163) was not opened; population-specific BMI cut-offs are therefore not encoded.
source not opened,
who2004_asian_bmi
Source not opened.
Review
No review recorded yet.