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Exact Dx synthetic data · demonstration
Extended criteria (experimental). This is the broader ten-condition engine, kept as a secondary area. It shows ICD-10-CM codes and illustrative grouping effects for CDI staff. The primary surface is Before you sign (kidney, measurement only). All extended pages.

← Back to the worklist · Whole encounter ENC-00092

Pilar Kestrel: Sepsis

ENC-00092 · 78M · Hospital Medicine · admitted Sat Oct 31, 2026 11:04 AM · discharged Sat Nov 07, 2026 11:56 AM · attending Dr. Cyrus Ellingham

Clinical judgement required Clinical judgement required Open Contested definitions (Sepsis-2 vs Sepsis-3)

Clinical judgement required: Definition-dependent: 3 SIRS criteria (Sepsis-2 met) but SOFA change only 0 (Sepsis-3 not met).

Documented vs supported

Documented
“sepsis” · A41.9 Sepsis, unspecified organism
Criteria support
no conclusion: clinical judgement required
Outcome
Definition-dependent: 3 SIRS criteria (Sepsis-2 met) but SOFA change only 0 (Sepsis-3 not met)
Rule
Sepsis (clinical validation; Sepsis-3 and Sepsis-2 shown side by side) v2026.11-1
Published source
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3), Singer et al., JAMA 2016;315:801-810 (2016), Boxes 3-4: sepsis = infection + acute change in total SOFA >=2 (baseline 0 unless known); septic shock = vasopressors for MAP >=65 and lactate >2 mmol/L despite adequate volume · source (checked 2026-11-14)
Contested
CONTESTED DEFINITIONS. Sepsis-3 (organ dysfunction, SOFA) is the current consensus definition; Sepsis-2 (SIRS) is still used by the CMS SEP-1 quality measure and by many payers' clinical-validation policies. When the two disagree this rule never concludes: it returns "clinical judgement required (definition-dependent)". ICD-10-CM guideline I.A.19: code assignment is based on the provider's statement, not on clinical criteria; clinical validation is a separate process. The rule validates documented sepsis only and never prompts for an undocumented sepsis diagnosis.

Clinical judgement required. The rule does not conclude here. A CDI specialist may send an open query or dismiss the finding; nothing is proposed as fact.

Effect if the clinician agrees (illustrative)

Change
no projected change (clinician judgement)
Secondary-diagnosis level
principal → —
MS-DRG (illustrative)
871 Septicemia or severe sepsis without MV >96 hours with MCC → 871 Septicemia or severe sepsis without MV >96 hours with MCC
Relative weight
1.9425 → 1.9425 (+0.0000)
Codes before
A41.9, J18.9, E66.813, E11.9, E78.5
Codes after
A41.9, J18.9, E66.813, E11.9, E78.5

All open gaps on this encounter together: MS-DRG 871 → 871 (RW +0.0000). The grouping does not change; the record becomes accurate.

CC/MCC status, CC exclusions (subset) and relative weights from the public CMS FY2026 IPPS final rule tables (5, 6I, 6J, 6K). This is not a grouper and not a payment estimate. Queries never mention any of this.

Severity documentation index change SIMULATED

0.0 points

SIMULATED: Illustrative severity weights (MCC = 1.0, CC = 0.5, non-CC = 0) summed over secondary diagnoses; not a validated risk-adjustment model and not a measured effect.

Evidence

Structured values are read by code from the cited rows. Note facts are shown only when the model's quote was found verbatim in the note.

Evidence (each item cited to a source row or a quoted span)
InputValueSource
Infection quoted from a note or an infection principal diagnosis True
“left lower lobe pneumonia” · History and physical DOC-000313, p. 1, line 5 · quoted span verified
Show the quote in the note
… 26-10-31 11:04 Service: Hospital Medicine Attending: Dr. Cyrus Ellingham History of present illness: 78-year-old man admitted with sepsis. Chest x-ray shows left lower lobe pneumonia; blood cultures drawn and ceftriaxone started. Past medical history: type 2 diabetes, hyperlipidemia. Review of systems otherwise negative. Exam: Lungs: clear …
principal diagnosis A41.9 · encounter ENC-00092
Highest temperature, first 48 h (C) 39.2
temperature 39.2 °C · vital VIT-009037 · 2026-11-01 11:24
Lowest temperature, first 48 h (C) 38.7
temperature 38.7 °C · vital VIT-009041 · 2026-11-01 19:24
Highest heart rate, first 48 h 121.0
heart rate 121/min · vital VIT-009042 · 2026-11-01 19:24
Highest respiratory rate, first 48 h 18.0
respiratory rate 18/min · vital VIT-008982 · 2026-10-31 11:24
Highest WBC, first 48 h (x10^3/uL) 18.6
WBC 18.6 x10^3/uL · lab LAB-003146 · 2026-11-02 05:00
Lowest WBC, first 48 h (x10^3/uL) 15.08
WBC 15.08 x10^3/uL · lab LAB-003142 · 2026-10-31 12:04
Lowest platelets, first 48 h (x10^3/uL) 225.0
platelets 225 x10^3/uL · lab LAB-003145 · 2026-11-01 05:00
Highest bilirubin, first 48 h (mg/dL) 0.76
bilirubin 0.76 mg/dL · lab LAB-003158 · 2026-10-31 12:04
Lowest mean arterial pressure, first 48 h (mmHg) 81.0
MAP 81 mmHg · vital VIT-009031 · 2026-10-31 19:24
Highest norepinephrine-equivalent dose, first 48 h (mcg/kg/min)
no vasopressor in the first 48 hours
0.0 derived (no vasopressor in the first 48 hours)
Lowest Glasgow Coma Scale, first 48 h 15.0
GCS 15 · vital VIT-009028 · 2026-10-31 11:24
Highest creatinine, first 48 h (mg/dL) 2.65
creatinine 2.65 mg/dL · lab LAB-003118 · 2026-10-31 12:04
Baseline creatinine (mg/dL), for the baseline renal SOFA score
most recent pre-admission value within 365 days
2.54
creatinine 2.54 mg/dL (pre-admission) · lab LAB-003117 · 2026-09-20 10:05
Rule trace (inputs, thresholds, outcome)
Rule trace (rule sepsis v2026.11-1; evaluated in order, first true outcome wins; "unknown" = missing input)
StepExpressionInputs and thresholds readResult
derived: sirs_temp coalesce(temp_max_48h > t.t_hi, false) or coalesce(temp_min_48h < t.t_lo, false) t.t_hi=38, t.t_lo=36, temp_max_48h=39.2, temp_min_48h=38.7 true
derived: sirs_hr coalesce(hr_max_48h > t.hr, false) hr_max_48h=121.0, t.hr=90 true
derived: sirs_rr coalesce(rr_max_48h > t.rr, false) or coalesce(paco2_min_48h < t.paco2, false) paco2_min_48h=unknown, rr_max_48h=18.0, t.paco2=32, t.rr=20 false
derived: sirs_wbc coalesce(wbc_max_48h > t.wbc_hi, false) or coalesce(wbc_min_48h < t.wbc_lo, false) or coalesce(bands_max_48h > t.bands, false) bands_max_48h=unknown, t.bands=10, t.wbc_hi=12, t.wbc_lo=4, wbc_max_48h=18.6, wbc_min_48h=15.08 true
derived: sirs_count count(sirs_temp, sirs_hr, sirs_rr, sirs_wbc) sirs_hr=True, sirs_rr=False, sirs_temp=True, sirs_wbc=True 3
derived: sofa_resp coalesce(case(pf_min_48h < 100 and adv_resp_support, 4, pf_min_48h < 200 and adv_resp_support, 3, pf_min_48h < 300, 2, pf_min_48h < 400, 1, 0), 0) adv_resp_support=False, pf_min_48h=unknown 0
derived: sofa_coag coalesce(case(platelets_min_48h < 20, 4, platelets_min_48h < 50, 3, platelets_min_48h < 100, 2, platelets_min_48h < 150, 1, 0), 0) platelets_min_48h=225.0 0
derived: sofa_liver coalesce(case(bili_max_48h >= 12, 4, bili_max_48h >= 6, 3, bili_max_48h >= 2, 2, bili_max_48h >= 1.2, 1, 0), 0) bili_max_48h=0.76 0
derived: sofa_cardio coalesce(case(norepi_max_48h > 0.1, 4, norepi_max_48h > 0, 3, map_min_48h < 70, 1, 0), 0) map_min_48h=81.0, norepi_max_48h=0.0 0
derived: sofa_cns coalesce(case(gcs_min_48h < 6, 4, gcs_min_48h < 10, 3, gcs_min_48h < 13, 2, gcs_min_48h < 15, 1, 0), 0) gcs_min_48h=15.0 0
derived: sofa_renal coalesce(case(creat_max_48h >= 5, 4, creat_max_48h >= 3.5, 3, creat_max_48h >= 2, 2, creat_max_48h >= 1.2, 1, 0), 0) creat_max_48h=2.65 2
derived: sofa_renal_baseline coalesce(case(creat_baseline >= 5, 4, creat_baseline >= 3.5, 3, creat_baseline >= 2, 2, creat_baseline >= 1.2, 1, 0), 0) creat_baseline=2.54 2
derived: sofa_delta sofa_resp + sofa_coag + sofa_liver + sofa_cardio + sofa_cns + sofa_renal - sofa_renal_baseline sofa_cardio=0, sofa_cns=0, sofa_coag=0, sofa_liver=0, sofa_renal=2, sofa_renal_baseline=2, sofa_resp=0 0
derived: sepsis3 infection_documented and sofa_delta >= t.sofa_delta infection_documented=True, sofa_delta=0, t.sofa_delta=2 false
derived: sepsis2 infection_documented and sirs_count >= t.sirs_min infection_documented=True, sirs_count=3, t.sirs_min=2 true
derived: shock sepsis3 and norepi_max_48h > 0 and coalesce(lactate_max_48h > t.lactate, false) lactate_max_48h=unknown, norepi_max_48h=0.0, sepsis3=False, t.lactate=2 false
outcome: no_infection not infection_documented infection_documented=True false
outcome: septic_shock shock shock=False false
outcome: both sepsis3 and sepsis2 sepsis2=True, sepsis3=False false
outcome: sepsis3_only sepsis3 sepsis3=False false
outcome: definitions_disagree sepsis2 sepsis2=True true

Documentation query

Title and question drafted by model clockworks-mock (audit entry #2147); clinical indicators and answer options assembled by code from the rule and the record.

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DOCUMENTATION QUERY (draft)
Title: Clarification request: infection-related documentation
Encounter: ENC-00092   Patient: Pilar Kestrel   To: Dr. Cyrus Ellingham

Clinical indicators from the health record:
- Documented in the record: "sepsis" [History and physical DOC-000313]
- "left lower lobe pneumonia" (2026-10-31 14:04) [History and physical DOC-000313, p. 1, line 5]
- principal diagnosis A41.9 [encounter ENC-00092]
- temperature 39.2 °C (2026-11-01 11:24) [vital VIT-009037]
- temperature 38.7 °C (2026-11-01 19:24) [vital VIT-009041]
- heart rate 121/min (2026-11-01 19:24) [vital VIT-009042]
- respiratory rate 18/min (2026-10-31 11:24) [vital VIT-008982]
- WBC 18.6 x10^3/uL (2026-11-02 05:00) [lab LAB-003146]
- WBC 15.08 x10^3/uL (2026-10-31 12:04) [lab LAB-003142]
- platelets 225 x10^3/uL (2026-11-01 05:00) [lab LAB-003145]
- bilirubin 0.76 mg/dL (2026-10-31 12:04) [lab LAB-003158]
- MAP 81 mmHg (2026-10-31 19:24) [vital VIT-009031]
- GCS 15 (2026-10-31 11:24) [vital VIT-009028]
- creatinine 2.65 mg/dL (2026-10-31 12:04) [lab LAB-003118]
- creatinine 2.54 mg/dL (pre-admission) (2026-09-20 10:05) [lab LAB-003117]

Question:
Could you review the indicators above and clarify the status of the documented infection-related diagnosis?

Response options (select one or write your own):
( ) Sepsis (please document the associated organ dysfunction, if any)
( ) Other (please specify): ____________
( ) Unable to determine

Please respond based on your independent clinical judgement. Any response, including "unable to determine", is acceptable. This query and your response are kept as part of the health record.

Other findings on this encounter

History

Audit entries for this finding (newest first)
SeqWhen (UTC)ActorAction EntitiesDecision / reasonModel / hashes
2147 2026-11-14T20:57:24 system:llm
system
llm.call ENC-00092, ENC-00092.sepsis — clockworks-mock mock-1/exactdx.draft_query@1
prompt 4fe3158ae3fe
output aa58f88e62fe
entry 99fb476c7869
1321 2026-11-14T19:24:30 system:llm
system
llm.call ENC-00092, ENC-00092.sepsis — clockworks-mock mock-1/exactdx.draft_query@1
prompt 4fe3158ae3fe
output aa58f88e62fe
entry 34f3504e6708
579 2026-11-14T18:29:05 system:llm
system
llm.call ENC-00092, ENC-00092.sepsis — clockworks-mock mock-1/exactdx.draft_query@1
prompt 4fe3158ae3fe
output aa58f88e62fe
entry 832cc44600ea